The molecular world of proteins, DNA, and living cells is becoming increasingly accessible to quantitative investigations: biophysical tools such as microscopy, nanoscopy, and optical manipulation provide us with nanoscopic hands and eyes to unravel the mysteries of this intriguing world. These single-molecule tools now enable us to directly observe and probe how essential processes such as DNA replication, transcription, and repair play out in real life and in real time.

My research is motivated by the drive to:

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