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Contact information
dr.ir.
Erwin J.G. Peterman
Vrije Universiteit Amsterdam
Department of
physics and astronomy
De Boelelaan
1081
1081 HV Amsterdam
The Netherlands
phone: +31 (0)20 598 7576
fax: +31 (0)20 598 7991
email: erwinp@nat.vu.nl
office: T068A |
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Research
interests
Overall, I am interested in how protein structural
dynamics are related to their function. The techniques I use to obtain this
information are (single-molecule) fluorescence microscopy, fluorescence
spectroscopy and optical tweezers.
More in particular, my students and me are working on
the following projects:
- How are conformational changes in the motor protein
kinesin coupled to its processive motion?
- How do kinesins and other microtubule-associated
proteins bring about their cellular tasks in mitosis and intracellular
transport?
- How do DNA-processing proteins (like recombinases, restriction
enzymes and polymerases) process DNA?
- How do chaperonins help proteins to fold?
- Is it possible to combine optical tweezers and
single-molecule fluorescence?
- How can we observe single biomolecules in cells and
multicellular organisms?
- How can we improve the sensitivity, resolution, imaging
depth and functionality of current microscopy methods?
For more information check the
research pages of the physics of complex systems group.
My research is funded by a grants from ALW, FOM and NWO.
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